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arthegall + genomics   221

Goodarzi et al. "Systematic discovery of structural elements governing stability of mammalian messenger RNAs" (Nature)
I'll be honest, I still shudder when I see the name "Saeed Tavazoie". (cf. http://www.ncbi.nlm.nih.gov/pubmed/15084257 )
saeed-tavazoie  genomics  expression-from-sequence  nature  research-article  personal 
10 days ago by arthegall
Need, Shashi et al. "Clinical application of exome sequencing in undiagnosed genetic conditions," Journal of Medical Genetics (2012)
"This study provides evidence that next-generation sequencing can have high success rates in a clinical setting, but also highlights key challenges. It further suggests that the presentation of known Mendelian conditions may be considerably broader than currently recognised." -- Looks like the authors are from Duke Medical School...
research-article  sequencing  exomes  clinical-genetics  biology  genetics  genomics  mendelian-disease 
11 days ago by arthegall
Stahl etl al. "Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis," Nature Genetics (2012)
"Our results are consistent with simulated genetic models in which hundreds of associated loci harbor common causal variants and a smaller number of loci harbor multiple rare causal variants. These analyses suggest that GWAS will continue to be highly productive for the discovery of additional susceptibility loci for common diseases."
gwas  genetic-testing  arthritis  genetics  genomics  research-article  nature-genetics 
13 days ago by arthegall
Stratakis, “Patients Can Have as Many Gene Variants as They Damn Well Please”: Why Contemporary Genetics Presents Us Daily with a Version of Hickam's Dictum," Journal of Clinical Endocrinology and Metabolism (2012)
Sorta feel like this is a misinterpretation of Occam's Razor, but it's still an interesting article.
review-article  genetics  occams-razor  hickams-dictum  genomics  genetic-variation 
13 days ago by arthegall
The Infinitely Many Genes Model for the Distributed Genome of Bacteria
Via Jonathan Eisen's blog
via:jonathan-eisen  bacteria  genomics  quantitative-biology  awesome 
15 days ago by arthegall
Fan, Li, "Test driving genome assemblers" (Nature Biotechnology)
More "comparison of genome assemblers" stuff. Related to the "comparison of genome annotations" linked to earlier.
genomics  assembly  sequence-analysis  review-article  nature-biotechnology 
17 days ago by arthegall
Richardson, Watson, "The automatic annotation of bacterial genomes" (Briefings in Bioinformatics)
The discussion of errors in annotation being propagated by basing one annotation on an earlier, erroneous or hypothetical annotation is excellent.
annotation  bacteria  genomics  bioinformatics  review-article 
18 days ago by arthegall
ArrayTrack™—a microarray database, data analysis & interpretation tool
Why does the FDA have its own microarray management platform? And what's with the (™) after the name? (A quick search at the USPTO website, [ http://tess2.uspto.gov/bin/gate.exe?f=login&p_lang=english&p_d=trmk ], reveals nothing by that name...)
fda  government  microarrays  data  database  web  genomics  wtf 
4 weeks ago by arthegall
[1204.3941] A Log-Linear Graphical Model for Inferring Genetic Networks from High-Throughput Sequencing Data
via:cshalizi  arxiv  research-article  graphical-models  regulatory-networks  genomics  machinelearning 
4 weeks ago by arthegall
Cell - Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes
The "Personal Omics" paper.
cell  research-article  genomics  personalized-medicine  personal-genomics 
4 weeks ago by arthegall
Translation: The twenty-first amino acid : Article : Nature
Overview of seleno-cysteines. (Where can I find comprehensive SECIS element predictions in human?)
genomics  genetics  seleno-cysteine  review  biology 
4 weeks ago by arthegall
MINiML
"MINiML (MIAME Notation in Markup Language, pronounced 'minimal') is a data exchange format optimized for microarray gene expression data, as well as many other types of high-throughput molecular abundance data."
xml  file-format  ncbi  geo  work  bioinformatics  data  genomics 
4 weeks ago by arthegall
Schadt, Woo, and Hao, "Bayesian method to predict individual SNP genotypes from gene expression data"
"We show that, not only can genotypic barcodes be derived from individual gene expression data sets that can in turn be used to identify the genotype vector corresponding to the given individual, but such barcodes also have the potential to reliably identify first-degree relatives and even reconstruct nuclear pedigrees directly from gene expression data." -- I think that the logical possibility of doing this is pretty obvious to anyone who's thought this data through (and there are a *lot* more examples of similar kinds of re-identification possible out there), but it's still awesome to see it actually carried out and demonstrated on real data.
genomics  eric-schadt  privacy  genotype  research-article  bioinformatics  data 
6 weeks ago by arthegall
Barretina et al. "The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity" (Nature)
An important new dataset. (Here is the site, from the Broad, where you can browse/download the data: http://www.broadinstitute.org/ccle/home ).
research-article  cancer  cle  nature  genomics  broad  novartis  work  drug-sensitivity  pharma  drug-discovery 
7 weeks ago by arthegall
Genome Medicine | Full text | Locus Reference Genomic sequences: an improved basis for describing human DNA variants.
One of the original papers on LRG-- check out boxes 1-3, which provide great canned use-cases for variant naming and coordinate/version handling.
genomics  bioinformatics  locus-reference-genomic  research-article  sequence-variants  data-management 
8 weeks ago by arthegall
PLoS ONE: iCanPlot: Visual Exploration of High-Throughput Omics Data Using Interactive Canvas Plotting
*One* figure (and a scatter plot, no less) in a paper about "visualization?" Meh.
visualization  genomics  plos-one  graphics 
10 weeks ago by arthegall
SRA format - SEQanswers
"Guys from NCBI said me that they don't give this documentation anybody. And if you want to use the SRA format then you need to use their API." -- Eeeesh, really?? That's pretty terrible.
public-domain  science  open-access  open-source  sra  genomics  ridiculous 
february 2012 by arthegall
PLoS ONE: Transcriptomic Analysis of Toxoplasma Development Reveals Many Novel Functions and Structures Specific to Sporozoites and Oocysts
"A single felid host is capable of shedding millions of oocysts, which can survive for years in the environment, are resistant to most methods of microbial inactivation during water-treatment and are capable of producing infection in warm-blooded hosts at doses as low as 1–10 ingested oocysts." --- Shudder.
toxoplasma-gondii  feline-behavior  cat-person  plos-one  research-article  biology  genomics  awful 
february 2012 by arthegall
Zhi, Chen "Statistical Guidance for Experimental Design and Data Analysis of Mutation Detection in Rare Monogenic Mendelian Diseases by Exome Sequencing" (PLoS ONE)
"... we present a statistical modeling framework to calculate the power, the probability of identifying truly disease-causing genes, under various inheritance models and experimental conditions, providing guidance for both proper experimental design and data analysis."
sequencing  plos  research-article  genomics  mendelian-disease  statistics  to-read 
february 2012 by arthegall
PLoS ONE: Improving Transmission Efficiency of Large Sequence Alignment/Map (SAM) Files
compression  file-format  bioinformatics  genomics  sequence-analysis  research-article  plos-one 
january 2012 by arthegall
[1011.5287] Distributed Storage Allocations
"By using an appropriate code, successful recovery can be achieved whenever the total amount of data accessed is at least the size of the original data object. The goal is to find an optimal storage allocation that maximizes the probability of successful recovery."
coding  arxiv  research-article  genomics  idea  storage  data 
december 2011 by arthegall
Baldi, Barionio, et al. "Countering Gattaca: Efficient and Secure Testing of Fully-Sequenced Human Genomes (Full Version)"
bioinformatics  genomics  privacy  research-article  gattaca  genetic-testing 
november 2011 by arthegall
Drug2Gene
Aggregates public data sources.
pharma  genomics  drug-discovery  public  database 
november 2011 by arthegall
Exome 80x - 23andMe
Tempting.
exome  genomics  23andme  pilot  personalized-genomics  personalized-medicine 
september 2011 by arthegall
Wiring the Brain: Welcome to your genome
genomics  genetics  variation  disease  snps  mutation 
august 2011 by arthegall
Baggerly and Coombes, "Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology" (arXiv)
The paper that knocked down the "genomic signatures" paper (doi:10.1038/nm1491).
science  retraction  bioinformatics  genomics  chemotherapeutics  scandal 
august 2011 by arthegall
Home - Clinical Genomics - LibGuides at Harvard Medical School - Countway Library of Medicine
Bibliography resulting from that symposium last December.
clinical-bioinformatics  bibliography  index  papers  list  medicine  genomics 
june 2011 by arthegall
Partek Incorporated | Next Generation Sequencing Software
Commercial software for NGS analysis. Listing software here so I know what external alternatives my (internal) customers might choose to buy, instead of using what we're writing for them for free.
bioinformatics  software  commercial-software  sequencing  sequence-analysis  genomics  ngs 
june 2011 by arthegall
Hopkins, Groom, "The druggable genome" : Article : Nature Reviews Drug Discovery
(doi:10.1038/nrd892) People keep talking about this paper at work -- and Hopkins gave one of the plenaries at IDD this year. I think what this is, is just mapping a lot of the intermediate data that's useful for drug discovery down on to the "genomic coordinate system," and making it available in one location for browsing. Not sure how useful that really is; does it omit something key?
research-article  drug-discovery  genomics  science  annotation  nature  review 
may 2011 by arthegall
Guttman et al. "Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs" (Nature Biotech, 2010)
The research article behind Scripture.
research-article  nature  aviv-regev  broad-institute  transcription  genomics 
may 2011 by arthegall
Home | www.broadinstitute.org/software/scripture
Yet another "transcript recovery from NGS" software package.
transcription  genomics  broad-institute  software  tophat  bioinformatics 
may 2011 by arthegall
Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
The paper that develops the GISTIC scoring method for genomic variation in cancer. This is showing up more and more frequently in some of what I'm dealing with at work, so time to read up on it...
gistic  cancer  genomics  research-article  genetic-variation  genetics 
may 2011 by arthegall
Integrative Genomics Viewer
The Broad's Java-based thick-client for genome visualization.
genomics  visualization  data  broad-institute  software 
may 2011 by arthegall
Database of Genomic Variants
To download.
data  bioinformatics  oncology  cancer  genomics  genomic-variation 
april 2011 by arthegall
Tumour evolution inferred by single-cell sequencing : Nature : Nature Publishing Group
cancer  oncology  tumor  genomics  sequencing  nature  research-article  via:in-the-pipeline 
april 2011 by arthegall
QIIME: Quantitative Insights Into Microbial Ecology — Homepage
Microbial ecology and biology through deep-sequencing toolkit
tool  bioinformatics  software  microbes  ecology  genomics 
march 2011 by arthegall
GenomeQuest, Inc.
Hmm... looks a little hinky, but what do I know?
next-generation-sequencing  bioinformatics  work  data  genomics 
march 2011 by arthegall
Diploid Human Genome Browser | HuRef 1.0 | Home
The genome viewer that Nelson worked on.
genome-browse  data  genomics  work  visualization  bioinformatics 
february 2011 by arthegall
PLoS ONE: Abundant Human DNA Contamination Identified in Non-Primate Genome Databases
If the contamination is from the researchers who collected or manipulated the samples, does that mean that we should be having them sign medical consent forms before publishing their data in public repositories? I'm only half-joking.
consent  bioinformatics  genomics  dna  contamination  plos  research-article 
february 2011 by arthegall
LRG - Home
Locus/Reference/Genomic -- this is the complement to RefSeqGene, building stable identifiers for loci independent of "gene identifier" or "genome build."
genomics  data  ncbi  locus  bioinformatics 
february 2011 by arthegall
SRA (Sequence Read Archive) : Studies : Browse : ERP000001 (Population genomics of domestic and wild yeasts)
"S. paradoxus populations are well delineated along geographic boundaries, whereas the variation among worldwide S. cerevisiae isolates shows less differentiation and is comparable to a single S. paradoxus population. Rather than one or two domestication events leading to the extant baker's yeasts, the population structure of S. cerevisiae consists of a few well-defined, geographically isolated lineages and many different mosaics of these lineages, supporting the idea that human influence provided the opportunity for cross-breeding and production of new combinations of pre-existing variations."
yeast  bioinformatics  genomics  metagenomics  sra  sequencing  project  from delicious
january 2011 by arthegall
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
The bowtie paper.
alignment  sequencing  research-article  genomics  bowtie 
december 2010 by arthegall
SybilGuard
Understanding "sibyl attacks" in social networks is, I think, one part of understanding privacy and anonymity in a setting where genetic information is being passed around or compared in a centralized system.
security  privacy  genomics  genetics  personalized-medicine  research-article  sybil-attacks  social-networks 
december 2010 by arthegall
Interactive Biosoftware - Practical software for bioscientists
This looks kinda bespoke (have I mentioned how 'bespoke' is my new favorite word?) and ad hoc, but ... mentioned during the Clinical Bioinformatics Seminar two weeks ago.
bioinformatics  software  tool  mutations  genetics  variation  genomics 
december 2010 by arthegall
The Great DNA Data Deficit: Are Genes for Disease a Mirage? (Jonathan Latham and Allison Wilson)
No, no, a thousand times no. GWAS may have been a load of optimistic over-sold crap, buried under a mountain of hype ... but this is a *terrible* essay, not worth the e-paper it's not printed on.  (And holding up Nicholas Wade, of all people, as a scientific visionary...) 
craziness  genetics  medicine  gwas  genomics  begging-the-question 
december 2010 by arthegall
Fong et al. "GWAS Analyzer: integrating genotype, phenotype and public annotation data for genome-wide association study analysis" (Bioinformatics, 2010)
gwas  genomics  genetics  data  bioinformatics  journal-article 
december 2010 by arthegall
CCDS Report for Consensus CDS
"The Consensus CDS (CCDS) project is a collaborative effort to identify a core set of human and mouse protein coding regions that are consistently annotated and of high quality. The long term goal is to support convergence towards a standard set of gene annotations."
genomics  genetics  ncbi  cds  curation  annotation 
december 2010 by arthegall
Kohane, Masys, Altman, "The Incidentalome: A Threat to Genomic Medicine", (JAMA 2006)
[JAMA, July 12, 2006, Kohane et al. 296 (2): 212] -- via Jonathan Eisen's twitter.
via:jonathan-eisen  omics  zak-kohane  opinion  editorial  genomics  personal-genomics  genetic-testing  genetics 
november 2010 by arthegall
HMS - Countway Library of Medicine - Director's Blog: Holding our breath for this diabetes risk
"It also suggests that we have insufficiently taken advantage of freely available public data to pursue relevant and timely medical research."
medicine  health  public-data  genomics  gwas  diabetes  evidence-based-medicine  zak-kohane 
november 2010 by arthegall
SBOL visual - SBOL
Visual icons for synthetic bio design. Perhaps useful in a wider context for genomic viz stuff? I asked about licensing for the actual image files, since there's no word (AFAICT) about it on the webpage. (One of the BioBrick RFCs asserts copyright to the BioBrick foundation, so there's that.)
biobricks  synthetic-biology  visualization  genomics  genetics  sbol 
november 2010 by arthegall
Omics! Omics!: Scenes from the Cancer Personalized Medicine Wilderness
"On the other hand, the regulatory environment is fraught with uncertainty and most likely this sort of organization will have to rely on wealthy customers willing to pay their own way."
n-of-one  personalized-medicine  genomics  cancer  health 
october 2010 by arthegall
Taverna - open source and domain independent Workflow Management System
workflow  taverna  science  genomics  mygrid  java 
october 2010 by arthegall
PLoS Currents: Evidence on Genomic Tests - a collection by PLoS
plos  plos-one  plos-currents  genomics  medicine  personalized-medicine 
october 2010 by arthegall
Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage — Genome Research
For cell-type annotation ... or, I don't know, just to read.
genomics  chip  methylation  sequencing  research-article  biology  differentiation  development  cell-types  stem-cells  via:arolfe 
october 2010 by arthegall
US clinics quietly embrace whole-genome sequencing : Nature News
genomics  sequencing  medicine  to-blog  nature-news 
october 2010 by arthegall
“Intellectual Property Rights and Innovation: Evidence from the Human Genome,” H. Williams (2010) « A Fine Theorem
The list of things that I need to blog about grows ... longer.  
to:blog  intellectual-property  innovation  genomics  celera  science  biology  craig-venter  via:cshalizi 
september 2010 by arthegall
OpenMicrobiome.org
"The Open Microbiome Initiative (OMI) will promote education, data integration, and potentially data acquisition efforts that advance this goal. Our vision: open datasets, tools and standards that everyone is encouraged to use and improve on to speed our understanding of the links between microbes and disease."
open  microbiome  rob-knight  genomics  data 
september 2010 by arthegall
Technology Review: Sequencing Tested as Infection Early Warning
Kinda want to see if I could work for these guys...
job  mit  technology-review  eric-schadt  pipe-dreams  bioinformatics  genomics  sensor-networks  infection  disease  menlo-park 
september 2010 by arthegall
Stats 329 - Winter 2009/2010
"Large Scale Simultaneous Inference"
class  statistics  genomics  inference  significance-testing  hypothesis-testing  course  notes 
september 2010 by arthegall
The Tree of Life: Summary of #iEVOBIO Day 1 #evolution #phylogenetics #informatics #opensource
"Phylogenomics of microbes: the dark matter of biology"
genomics  evolution  phylogenomics  rod-page  jonathan-eisen  conference  presentation  biology 
september 2010 by arthegall
EULER homepage
sequence-assembly  dna  genomics  pavel-pevzner  software 
september 2010 by arthegall
"Genetic Tests Get Mixed Results For Blood Thinners" (NPR.org)
To read. Personalized medicine in the news.
personalized-medicine  genomics  plavix  medicine  health  npr 
august 2010 by arthegall
"Independent Introduction of Two Lactase-Persistence Alleles into Human Populations Reflects Different History of Adaptation to Milk Culture"
Normally, lactase persistence ("LP") is associated with a particular SNP in an enhancer 13kb upstream of the lactase (LCT) gene. Here they show, though, that (as you might expect) there are other variants in different human subpopulations which give rise to the same phenotype. (I think this is the Broad's "ability to drink milk arose twice in human evolution" paper that I remember seeing touted on their Main St. display screens a year or two ago.)
milk  lactase  science  genomics  evolution  transcriptional-regulation  research-article 
august 2010 by arthegall
Conway and Bromage, "Succinct Data Structures for Assembling Large Genomes"
"Unfortunately, improvements in the computational feasibility for de novo assembly have not matched the improvements in the gathering of sequence data. This is for two reasons: the inherent computational complexity of the problem, and the in-practice memory requirements of tools. ... In this paper we use entropy compressed or succinct data structures to create a practical representation of the de Bruijn assembly graph, which requires at least a factor of 10 less storage than the kinds of structures used by deployed methods."
sequence-analysis  assembly  arxiv  via:vaguery  genomics  de-bruijn-graph  compression  data-structures 
august 2010 by arthegall
"SNPwatch: Uncertainty Surrounds Longevity GWAS" (The Spittoon)
The Spittoon (the blog from 23andme) does the follow-up on that fishy-smelling "here are a bunch of genetic variants associated with longevity" study that got all that press a few months ago.
23andme  spittoon  review  longevity  gwas  statistics  uncertainty  genomics  genetics  science  news 
august 2010 by arthegall
"Terabase metagenomics -- meeting and outlook" (Daily Life in an Ivory Basement)
"The meeting was focused on the promise of terabase metagenomics for a "whole earth" microbial ecology sampling projects, and we spent quite a lot of time trying to figure out the size of unknown unknowns in metagenomics. There was a great mix of people at the meeting -- both "pure" microbial ecologists who regarded computers with suspicion and computer scientists who didn't understand how DNA became protein, as well as the entire range between those two poles. We talked about questions such as: "how deep do we need to sequence in order to get a real picture of microbial diversity?" (a: very) and "how do we reconcile genomic and transcriptomic data sets?" (a: unknown) and "how can we scale up 1000-fold when our existing algorithms are all N-squared?" (a: with difficulty.) The discussion was at a reasonably high level of sophistication: pretty much everyone in the room had "seen the elephant", and representatives of the major analysis pipelines were also present."
metagenomics  genomics  futurism  biology  bacteria 
august 2010 by arthegall
Partners HealthCare Center for Personalized Genetic Medicine
via:arolfe  medicine  genomics  genetics  personalized-medicine  personalized-genomics  partners 
august 2010 by arthegall
"Distractions -- there's an app for that" (Omics! Omics!)
Keith Robison muses on what kind of app to develop for an Android device -- "Given that most of the datasets I work with now are enormous, it's hard to see any point to trying to access them via phone. A tiny browser for the UCSC genome database has some appeal, but that's sounding a bit ambitious."
android  mobile  programming  development  futurism  genomics  ideas  keith-robison 
july 2010 by arthegall
Leibler, Kussell, "Individual histories and selection in heterogeneous populations" PNAS
"Using “individual histories”—temporal sequences of all reproduction events and phenotypic changes of individuals and their ancestors—we present an alternative approach to quantifying selection in diverse experimental settings..."
via:cshalizi  pnas  selection  history  population-effects  genomics  research-article  statistics 
july 2010 by arthegall
"Time for Genetic Insurance" (Marginal Revolution)
"I originally discussed genetic insurance in Tabarrok, A. 1994. Genetic Testing: An Economic and Contractarian Analysis. Journal of Health Economics 13:75-91." -- To read.
alex-tabarrok  genetic-testing  genetics  medicine  genomics  personalized-genomics  insurance  health 
july 2010 by arthegall
New Scientist - 5th March 1987 "The race to map the human genome"
Picked up by Shaun...
Robert Weinberg (MIT): "I'm surprised consenting adults have been caught talking about it [sequencing the genome]... it makes no sense."
David Botstein (MIT): "I do not believe that there is any strong scientific justification for knowing the sequence of the entire human genome".

So, Shaun, do you think they (Botstein and Weinberg) have been proven right or wrong?
via:WanderingAengus  david-botstein  robert-weinberg  quotes  human-genome  genomics  futurism  science  biology 
june 2010 by arthegall
Expected Error Histograms from Illumina 36bp Reads « LingPipe Blog
illumina  sequencing  genomics  errors  lingpipe 
june 2010 by arthegall
PLoS ONE: Analysis of Antisense Expression by Whole Genome Tiling Microarrays and siRNAs Suggests Mis-Annotation of Arabidopsis Orphan Protein-Coding Genes
expression  microarrays  ncrna  plos-one  research-article  genomics  antisense-expression 
june 2010 by arthegall
Synthetic Bacterial Genome Takes Over Cell - NYTimes.com
Amazingly, Nicholas Wade appears to have gotten cautious or negative comments from David Baltimore, George Church, *and* Leroy Hood -- a trifecta, of sorts.
nicholas-wade  nytimes  science  journalism  george-church  craig-venter  synthetic-biology  biology  news  genomics 
may 2010 by arthegall
Mondal et al. "Characterization of the RNA content of chromatin" (Genome Research 2010)
"To uncover the functional role of ncRNA in chromatin organization, we deep sequenced chromatin-associated RNAs (CARs) from human fibroblast (HF) cells. This resulted in the identification of 141 intronic regions and 74 intergenic regions harboring CARs. The intronic and intergenic CARs show significant conservation across 44 species of placental mammals."
chromatin  rna  genomics  ncrna  research-article  biology  via:arolfe 
may 2010 by arthegall
Coulombe et al. "Multiple Promoters and Alternative Splicing: Hoxa5 Transcriptional Complexity in the Mouse Embryo" (PLoS ONE)
transcription  regulation  genomics  biology  hox-genes  mouse  plos-one  research-article 
may 2010 by arthegall
Khachane and Harrison, "Mining Mammalian Transcript Data for Functional Long Non-Coding RNAs" (PLoS ONE)
plos-one  research-article  mammals  ncrna  transcription  genomics 
may 2010 by arthegall
Avise, "Footprints of nonsentient design inside the human genome" (PNAS)
Cute.
evolution  science  religion  pnas  genomics  genetics  development 
may 2010 by arthegall
"The next five years of computational genomics at NHGRI" (Cryptogenomicon)
"Plan explicitly for sustainable exponential growth. We keep using metaphors of data “tsunamis” or “explosions”, but these metaphors are misleading. Big data in biology is not an unexpected disastrous event that we have to clean up after. The volume of data will continue to increase exponentially for the foreseeable future. We must make sober plans for sustainable exponential growth (this is not an oxymoron)." -- Sean Eddy's words are always Words of Wisdom.
sean-eddy  nih  futurism  genomics  data  sequencing 
may 2010 by arthegall
PLoS Computational Biology: A Primer on Metagenomics
To read.
plos  bioinformatics  metagenomics  genomics  primer  biology 
april 2010 by arthegall
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