Dundee University scientists have made a major breakthrough that could stop devastating Parkinson's disease ''in its tracks''.

BMW has released details on its refreshed 2013 7 Series flagship before it goes on sale late this summer. But while the new drivetrains, mildly updated exterior and reworked interior are nice, what’s more impressive is the latest iteration of BMW iDrive. And we’ve got an exclusive hands-on with the system.

Olive Oil Times is the most-read source of news, reviews and analysis on this fascinating subject. Our growing staff of expert contributors in every olive oil producing region provide timely information for consumers, industry professionals and olive oil enthusiasts.

And we’re just getting started. Just like this ever-evolving subject, we’ll never stop looking for new stories and innovative ways to share them.

Scientists at the Medical Research Council (MRC) Protein Phosphorylation Unit at the University of Dundee have discovered a new molecular switch that acts to protect the brain from developing Parkinson's disease.

Use of the antioxidant urate to protect against the neurodegeneration caused by Parkinson's disease appears to rely on more than urate's ability to protect against oxidative damage. In the May issue of the open-access journal PLoS One, researchers from the MassGeneral Institute for Neurodegenerative Diseases (MGH-MIND) describe experiments suggesting the involvement of a novel mechanism in urate's protection of cultured brain cells against Parkinson's-like damage.

Now researchers are turning to what would seem an unlikely source of a brain disorder: the gut.

"This area of research is really hot right now, and we think it's really important," said Dr. Kathleen Shannon, neurologist, Rush University Medical Center

There is growing evidence that Parkinson's disease may begin in the intestinal wall then spread to the brain.


"It's a game changer. First of all, it's a way to identify patients who have Parkinson's disease decades before they ever actually have the symptoms," said Jeffrey H. Kordower, Ph.D., neuroscientist, Rush University Medical Center.

In very small study, researchers at Rush University Medical Center examined tissue samples taken from patients during colonoscopies years before they showed any symptoms of Parkinson's. What the Rush scientists were looking for is something called alpha synuclein. It's a protein that accumulates in the brains of Parkinson's patients and is considered a pathologic hallmark of the disorder. It also seems to gather in the intestines.

"Even before the brain cells are infected the nerve cells in the wall of the intestines are affected with the same protein," said Dr. Shannon.

So how those proteins might get from the intestinal track to the brain is a mystery, but researchers suspect it's a very slow process, possibly taking years. Picking up signs of the protein through colonoscopy or sigmoidoscopy might one day be used to predict who's at risk for the disease, long before there is any damage in the brain.

Unique visual appeal, 3600 Circle Sound, Bluetooth music streaming, device charging – and more

Here we've rounded up several wireless Bluetooth speakers for your consideration. They work with all smartphones and tablets meeting the Advanced Audio Distribution Profile (A2DP) spec, including the Apple iPhone, iPad, and most Android devices, but keep in mind that Bluetooth causes limited loss in audio quality. For better sound, these devices can also play music from a non-Bluetooth device using the 3.5mm line-in port and a direct connection.

Any of them are excellent speakers to bring on your next trip, but I'm particularly impressed with the Jawbone Jambox and the Logitech Mini Boombox.
They're tough and portable, but you can also pair them with your phone's calling features to make a travel speakerphone.

Le Creative D100 est un boombox moderne qui diffuse un son sans fil à partir de n'importe quel périphérique sans fil compatible Bluetooth. Il offre un foule de possibilités, sans le handicap du câblage, et s'adapte harmonieusement à n'importe quel environnement où la musique est partagée, que ce soit sur une piste de skate ou à l'occasion d'une fête organisée à l'improviste sur la plage.

With on/off ideas and storage that uses the walls efficiently, a small bathroom can do more. In this tiny bathroom, for example, we managed to fit in all of the functions for doing laundry and still leave enough room to relax. It may not be a real spa, but in 2.7 square metres it's about as close as it gets.

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GlobalSpec has a global user base of more than 6,900,000 registered users; a user community that continues to grow by more than 80,000 new registrants each month. GlobalSpec is increasingly becoming "the place" where the engineering community gathers and conducts business.

Aside from trying to get Google+ on track and dealing with Penguin updates, Google’s Sergey Brin is working on a project that’s a little more personal to him, as well as those who suffer from Parkinson’s disease, a a degenerative disorder that attacks the central nervous system. The fight against Parkinson’s is personal to Brin because his family history, along with his DNA indicates he may contract the disease as he gets older.

Neuroscientist Patrik Verstreken of the Flanders Institute for Biotechnology, in collaboration with colleagues from Northern Illinois University, reported success in using vitamin K2 to undo the effect of one of the genetic defects that leads to Parkinson's.

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Top 15 Most Popular Science Websites | May 2012

Here are the 15 Most Popular Science Sites as derived from our eBizMBA Rank which is a constantly updated average of each website's Alexa Global Traffic Rank, and U.S. Traffic Rank from both Compete and Quantcast. "*#*" Denotes an estimate for sites with limited Compete or Quantcast data.

Since there are so many aggregators for the different operating systems, we have collected huge a list of Windows, Mac, Linux, web based, mobile and email based feed readers. All reffering links were last checked on April 27th 2012.

This list of Google products includes all major desktop, mobile and online products released or acquired by Google Inc. This list also includes prior products, that have been merged, discarded or renamed. Features within products, such as web search features, are not listed.

The Top 10 Tastiest Recipes Websites: Best of Food Online 2012

This is a list of environmental websites which are websites dealing with environmental issues.

Le candidat du Parti socialiste devient le 7e président de la Ve République. Il réunit, selon les derniers résultats et estimations tombés, entre 51 et 52% des voix. Les deux rivaux ont maintenant tenu leur discours.

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